Meet novartis management may 23, 2019 investor presentation. There is much variability in the expression of sickle cell disease scd and recent works suggest that environmental and social factors may also influence this variability. Download predesigned 0914 sickle cell anemia medical images for powerpoint powerpoint templates, ppt slides designs, graphics, and backgrounds at. Bring your friends, family, neighbors and coworkers.
Ppt sickle cell anemia powerpoint presentation free to. Out of the estimated population 4,353,8932 right diagnosis conducted a survey and concludes that the extrapolated incidence of sickle cell anemia patients was found to be 4,353 during the year 2014and death rate was found to be 0%. Discontinuing prophylactic transfusions used to prevent. Because children with scd are at an increased risk for infection and other health problems, early diagnosis and treatment are important. Johnson created with haiku deck, free presentation software that is simple. This helps you give your presentation on red blood cell morphology in a conference, a school lecture, a business proposal, in a webinar and business and professional. A vasoocclusive crisis occurs when the microcirculation is obstructed. Mar 14, 2014 powerpoint is the worlds most popular presentation software which can let you create professional red blood cell morphology powerpoint presentation easily and in no time. Anemia is a pathological condition characterized by lowering of the circulating red cell mass or hb concentration or both together below normal levels.
Powerpoint presentation for my structure of the human body course, winter 2015 on sickle cell disease. From our beginnings in 1927, carolina biological supply company has grown to become a leading supplier of science teaching materials for all levels of education. Molecular basis of sickle cell anemia ppt betterlesson. Powerpoint is the worlds most popular presentation software which can let you create professional red blood cell morphology powerpoint presentation easily and in no time. Mar 16, 2015 sickle cell anemia presentation tiffany taylor. One of the leading causes of death in children with sickle cell anemia is an acute splenic sequestration crisis. A presentation made about sickle cell disease by yara mostafa, yasser osama. Jan 29, 2020 sickle cell disease scd usually manifests early in childhood. Amino acid substitution in hbs ss gene homozygous ss one s gene sickle cell anemia, 80% to 100% of the hemoglobin is hbs sickle cell trait, 20% to 40% of the hemoglobin is hbs no symptoms under normal conditions.
Sickle cell presentation and free sickle cell trait. Apart from this, the report also provides the market outlook, growth, share, size, opportunity and forecast. Sickle cell presentation and free sickle cell trait screening. Sickle cell disease requires immediate medical attention because of the severity of the patients pain, which is caused by the sickle cells occluding small and sometimes large blood vessels. The sickle cell pain crisis is a common presentation encountered by many emergency departments and general medicine floors across the united states and abroad. Inheritance of sickle cell disease if one parent has sickle cell trait hbas and the other does not carry the sickle hemoglobin at all hbaa then none of the children will have sickle cell anemia. Infection or enlargement of the spleen, an organ that stores red blood cells, may make anemia worse. The most common clinical manifestation of scd is vasoocclusive crisis. Globally, the majority of persons born with sickle cell disease do not have access to hydroxyurea or more expensive interventions. Because of their irregular shape, sickled blood cells may become. Under hypoxic and other metabolic conditions, red blood cells containing hbs becomes rigid and develops a sickled shaped form. Oral and dental considerations in management of sickle cell. May 08, 20 sickle cell disease scd is the most common cause of stroke in children and one of the most devastating complications of scd. Sickle cell anemia sickle cell anemia is an inherited red blood cell disorder.
A 26 year old female patient presents to the emergency department with complaint of severe pain in the lower extremities. Allison 1954 slide 8 convergent evolution and malaria interesting correlations malaria and the world health organization evolution evolutionary arms race. Sickle cell anemia powerpoint presentation software. Facts you should know centers for disease control and. Signs and symptoms related to anemia the most common symptom of anemia is fatigue feeling tired or weak. Sickle cell anemia hbss most severe form of disease haemoglobin c hbsc haemoglobin e hbse haemoglobin s beta thalasseamiathis is a mild form of sickle disorder. Oral and dental considerations in management of sickle. More prevalent in those of african descent, mediterranean descent, and middle eastern descent. Normal red blood cells are round like doughnuts, and they move through small.
One thousand seventynine surgical procedures were conducted on 717 patients 77% sickle cell anemia ss, 14% sickle hemoglobin c disease sc, 5. Anemia by dilution associated with normal pregnancy. A mash up of highly useful educational information regarding the causes, treatments, and testimonials of families that are afflicted with this disease. Mar 15, 2015 powerpoint presentation for my structure of the human body course, winter 2015 on sickle cell disease. Called anemia, this oxygen deprivation often results in fatigue for the individual. Sickle cell anemia market research report forecast to 2025 the sickle cell anemia market report offers a complete picture of industry trends and factors along with quantitative data based on historical data and from various sources. Avoid overeating increase exercise intensity gradually reports signs of distress to atc linked to 10 onfield deaths during last decade family tree what else. Ppt sickle cell disease powerpoint presentation free to. Sickle cell anemia is an inherited blood disease that affects the red blood cells. Types of haemoglobinopathies sickle cell traits hbas adequate amount of normal haemoglobin is present, they are carriers, do not have symptoms of sickle cell disorder. This paper aims to use geographic information systems technology to examine the association between socioenvironmental exposures and health outcomes in all persons who have attended or currently.
Overview of sickle cell anemia pathophysiology springerlink. Sickle cell disease to compare the incidence of sickle cell disease in cameroon with its incidence in the united states and. Background physiology sickle cell disease occurs when an affected individual inherits hbs from both parents and has the resultant genotype of hbss. Sickle cell disease scd is a structural and monogenetic genetic. Clinical trials external icon uptodate information on sickle cell disease clinical research trials. Stroke causes substantial morbidity in children with sickle cell disease. Sickle cell disease scd is an inherited disorder characterized by a defect in the gene for hemoglobin. Mar 01, 2012 sickle cell disease is an inherited disorder of hemoglobin synthesis, which affects many individuals worldwide. May 26, 2012 sickle cell anemia describes homozygosity for hemoglobin s hbss while sickle cell disease describe all the conditions resulting from the phenomenon of sickling. Best powerpoint templates download your favorites today. For the first 6 months of life, infants are protected largely by elevated levels of hb f.
The shriveled blood cells of an individual with this disorder may break apart, causing a shortage in red blood cells, thus providing little oxygen to the body for usage. Athletes with sickle cell trait should be excluded from participation in performance tests such as mile runs, serial sprints, etc. Presentation and comparison of nine quaternary structures of. The genopro software version 2016 was used to make the. American sickle cell anemia association external icon information and support groups. Sickle cell disease influences the evolution of pregnancy with fetal and maternal consequences. Sickle cell disease singapore pdf ppt case reports. Take your hr comms to the next level with prezi video. Blood is slow and sluggish can lead to vaso occlusion of the vessel. American society of hematologys scd initiative external icon scd education, research, and policy resources.
Apart from this, the report also provides the market outlook, growth, share, size, opportunity and forecast during 20192025. There is a one in two 50% chance that any given child will get one copy of the hbas gene and therefore have the sickle cell trait. Sickle cell anemia is present at birth, but many infants dont show any signs until after 4 months of age. An ebook reader can be a software application for use on a. Clinical presentation of sickle cellhemoglobin c disease. Sickle cell anemia definition of sickle cell anemia by the. Human sickle cell anemia slide, smear, wrights stain. Ppt sickle cell disease powerpoint presentation free. Atypical presentation of sickle cell disease in an adult.
Sickle cell presentation and free s trait testing sickle. Blood transfusion policies for sickle cell disease in pregnancy. There is a one in two 50% chance that any given child will get the sickle cell. People with sickle cell disease have red blood cells erythrocytes that contain mostly hemoglobin s, an atypical molecule that causes the cells to have a sickle, or crescent, shape. Causes of death and early life determinants of survival in. A free powerpoint ppt presentation displayed as a flash slide show on id. The primary cause of disease pathophysiology is the deoxygenationinduced polymerization of the mutant sickle hemoglobin.
Anemia is a common effect of scd, but it can be treated. Sickle cell hepatopathy covers a range of hepatic pathologies arising from a wide variety of insults to the liver in patients with sickle cell disease. Microscope slide showing a human blood smear from a person with sickle cell anemia. Sickle cell powerpoint templates w sickle cellthemed. Statistical analyses were performed using r software version 2. Rapid analgesic management will help prevent the crisis from progressing to the point where hospitalization will be unavoidable. Sickle cell anemia results from a single amino acid substitution in the globin chain. Other signs and symptoms are linked to the diseases complications. This event is open to the public and free food will be provided.
There is also a one in four chance that any given child could be completely unaffected. Mar 27, 2012 sickle cell anemia is present at birth, but many infants dont show any signs until after 4 months of age. The most common signs and symptoms are linked to anemia and pain. It occurs mainly in patients with homozygous sickle cell anemia. Sickle cell anemia definition of sickle cell anemia by. Sickle cell disease and pregnancy dr sinou micyline epouse tchana kontchou gynecologue obstetricien postgraduate training in reproductive health research faculty of medicine, university of yaounde 2007. However, it is important to recognize that the pain in the sickle cell crisis is only the presenting symptom, and a variety of adverse events must be anticipated and addressed for all. Sufferers can also experience kidney problems, stroke, infections, bone and chest pains. Socioenvironmental exposures and health outcomes among. See more ideas about sickle cell anemia and sickle cell trait.
Haldane 1949 geographical distribution of malaria 2005 a. Sickle cell anemia is a genetic disease caused by replacement of glutamic acid by valine in position 6 at the nterminus of the betachain of globin, thus resulting in hemoglobin s. This event is open to the public and free food will be provided 1 in 12 african americans has sickle cell trait. Vasoocclusive, aplastic and sequestration crises are common in a sickle cell child. Microscope slide showing a human blood smear from a person with sickle cell anemia stained with wrights stain. Sickle cell anemia is an inherited disorder that leads to the production of an abnormal hemoglobin variant, hemoglobin s hbs hemoglobin s production arises from an altered mutated s gene. Cardiac iron overload in chronically transfused patients with. In 1953 green et al first described the hepatopathy developing in patients with sickle cell anemia in autopsy studies. Blood transfusions are used to treat severe anemia. History in the year 1904 cardiologist and professor of medicine james b herrick found peculiar elongated cells in blood of a 20 years old dental student who was. Amino acid substitution in hbs slide 4 slide 5 slide 6 rbcs have hbs slide 8 sickle cell. Prophylactic versus selective blood transfusion for sickle cell. Clinical presentation of sickle cellhemoglobin c disease early symptoms were observed in a representative sample of 166 children with slckle cellhemoglobin c dlsease dlagnosed at birth. Dear editor, sickle cell disease is an inherited disorder of hemoglobin synthesis, which affects many individuals worldwide.